Vaccines against herpes zoster, ‘shingles’, are located outside the SUS; new vaccine agent costs R $ 1,686 | Health

coverage Shingrix for prevention shinglesfrom the British pharmaceutical company GSK, arrives in Brazil almost a year after being regulated by the National Health Monitoring Agency (Anvisa) in August 2021.

It is administered in two doses, and within two months between applications, the manufacturer promises more than 90% effective in people over the age of 50, one of the target group of vaccines.

However, the vaccine is also recommended for adults over the age of 18 with a higher risk of infection, such as patients. immunity. This is the first time such a symptom has been found in the country. Prior to that, only MSD vaccine, Zostavax, was approved in Brazil, but not in the public domain.

No vaccine is available from the National Immunization Program, PNI. How full coverage costs 1,686 locations in the private market, see below what are the symptoms of vaccination and what are the prospects for inclusion in the public health system.

1) What are vaccine recommendations?

According to Anvisa, coverage GSK (Shingrix) and inactive viruses is shown for adults 50 years and older and adults 18 years of age and older at increased risk of shingles, usually people receiving cancer treatment, people living with HIV, who will go through bone marrow or organ transplantation, lupus, multiple sclerosis, etc.

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Already vaccinated MSD (Zostavax)produced by diminished viruses and approved by regulatory agency since early 2014, Not shown to the immune system.

According to the Brazilian Immunization Program (SBIm), it is 14 times the capacity of the varicella vaccine, and has been approved for single-dose use in adults called. incapable of immunity (which may trigger a normal immune response) over 50 years. The vaccine also showed immunity against shingles of around 69.8%.

Isabella Ballalai, SBIm vice-president, explains that just as osteoarthritis affects people with chickenpox, the vaccine is recommended for high-risk groups: those over the age of 50, especially those over 60, and those who are immune, without caring age.

“Vaccines are used to prevent osteoarthritis, post-herpetic neuralgia (chronic pain that can last for more than three months) and among other complications, such as facial paralysis,” explains the specialist. “And as the risk increases [de ter a doença]”.

Regarding adolescents, Ballalai notes that it is rare for patients who are not immune to infection.

Zostavax, MSD / MERCK vaccine against ost sores. Vaccination has not been shown in patients with weakened immunity. – Photo: UK Healthcare Organization / Disclosure

What is the disease and what are its symptoms?

Popular as brass, shingles has serious side effects if not diagnosed and treated quicklywhich can affect the nerve endings in the eyes, ear and face, causing paralysis, hearing and loss of vision.

A recent example is the story of singer Justin Bieber, who was diagnosed with Ramsey-Hunt syndrome, which is an ear infection.

The disease is caused by the virus that causes chickenpox (chickenpox), known as varicella-zoster, and is different from cold sores. The most common condition is affecting people with anemia or people whose immune systems are weakened, such as infections or other health problems.

According to the Ministry of Health, the main symptoms preceding the most common (and generally painful) skin lesions are the following.

  • nervous (neuralgic) pain;
  • paresthesias (nausea, vomiting, numbness, pressure, etc.);
  • internal burns and itching;
  • fever;
  • headache;
  • malaise.

Ballalai adds that shingles are NOT contagious to a person who is immune to chickenpox (like all those people who have had chickenpox)but that skin lesions that affect those with the virus can lead to chickenpox infection.

“You will not get a rash, now a child who has not had chickenpox and has not been vaccinated can get chickenpox from that adult. [que está com o vírus da varicella-zóster]”, says Ballalai.

How much do vaccines cost? How should they be managed?

The Shingrix (GSK) dosage schedule is two separate two-month vaccinations. The cost per request is R $ 843 (total reais 1,686).

Zostavax (MSD) is administered in a single dose, which costs an average of R $ 570.

“For those who have already taken the reduced vaccine (MSD), we recommend that they take the immunized vaccine (GSK), because the reduced vaccine generally protects for four years. It works best”, explains Ballalai. “And those who have had herpes zoster and are at risk should also be vaccinated, because the risk continues: the disease can come more than once.”

Vaccines are not available on PNI

GSK and MSD vaccines are not part of the National Immunization Program, PNI, which makes access difficult for those who need immunizations and cannot afford market prices.

For SBIm vice president, the inclusion of these vaccines in the public system is “always desirable”, especially for people over 60 years of age.

However, he points out that since this availability depends on a number of factors, such as cost-effectiveness studies, the best and most “quick” way could be to make these vaccines available at specialized Immunobiological Reference Centers (CRIE), public health and. free which provides vaccines that are not available in PNI for carriers of immunodeficiency.

O g1 questioned the Ministry of Health about the possibility of including the donors in the public system, but received no response from the ministry until the final update of this report.

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